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Regrow Your Hair, Starting Now
A New Science Now series from New Health & Longevity and Apple Poly LLC
Current Science on the
Hair Growth Promoting Effects of Green Tea Polyphenols
Green tea
polyphenols are only recently understood as positive factors in hair
growth and follicle health. They possess some of the same mechanisms of
action as procyanidins from apples, including:
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Inhibition of apoptosis (programmed cell death)
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Radioprotection/photoprotection of follicle cells
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Profound antioxidant activity
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Potential follicular inhibition of TGF-beta
In
addition, green tea polyphenols inhibit 5-alpha-reductase in the androgen
cascade, the same mechanism by which Propecia
affects hair loss, without side effects. Click on
the titles below for a more in-depth review of the science
behind these safe natural plant phytochemicals for hair growth.
| 1995 |
Liao S, Hiipakka RA., Ben
May Institute, University of Chicago, IL 60637, USA.
Selective inhibition of steroid 5 alpha-reductase isozymes by tea
epicatechin-3-gallate and epigallocatechin-3-gallate.
Biochem Biophys Res Commun. 1995 Sep 25;214(3):833-8. |
| 2002 |
Hiipakka RA, Zhang HZ,
Dai W, Dai Q, Liao S., Ben May Institute, University of Chicago, IL
60637, USA.
Structure-activity relationships for inhibition of human
5alpha-reductases by polyphenols.
Biochem Pharmacol. 2002 Mar 15;63(6):1165-76. |
| 2003 |
Kim SH, Kim SR, Lee HJ,
Oh H, Ryu SY, Lee YS, Kim TH, Jo SK.
Apoptosis in growing hair follicles following gamma-irradiation and
application for the evaluation of radioprotective agents.
In Vivo. 2003 Mar-Apr;17(2):211-4. |
| 2005 |
Esfandiari A, Kelley P.
The effects of tea polyphenolic compounds on hair loss among rodents.
J Natl Med Assoc. 2005 Jun;97(6):816-8. |
| 2006 |
Kwon OS, Han JH, Yoo HG,
Chung JH, Cho KH, Eun HC, Kim KH.
Human hair growth enhancement in vitro by green tea
epigallocatechin-3-gallate (EGCG).
Phytomedicine. 2006 Nov 6; |
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| Related
Studies- Oral Bioavailability |
Chow HH, et al, Arizona
Cancer Center, The University of Arizona, Tucson, Arizona 85724, USA.
Effects of dosing condition on the oral bioavailability of green tea
catechins after single-dose administration of Polyphenon E in healthy
individuals.
Clin Cancer Res. 2005 Jun 15;11(12):4627-33. |
Nakagawa K, Okuda S,
Miyazawa T., Faculty of Agriculture, Tohoku University, Sendai, Japan.
Dose-dependent incorporation of tea catechins,
(-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human
plasma.
Biosci Biotechnol Biochem. 1997 Dec;61(12):1981-5. |
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Related Studies- Photoprotection/Radioprotection |
Yusuf N, et al,
Department of Dermatology, University if Alabama at Birmingham,
Birmingham, AL USA.
Photoprotective effects of green tea polyphenols.
Photodermatol Photoimmunol Photomed. 2007 Feb;23(1):48-56. |
Uchida S, Ozaki M, Suzuki
K, Shikita M.
Radioprotective effects of (-)-epigallocatechin 3-O-gallate (green-tea
tannin) in mice.
Life Sci. 1992;50(2):147-52. |
| 99 more studies on
photoprotection of GTP |
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