Nature's Premier Antioxidant^TM

1-888-APPLE-FARM

Does DHT Really Cause Hair Loss? Maybe Not...

    Before we start today, I want to congratulate you.

    Why? Because you've made it this far. So I know you're really interested in what science can do for your hair loss problem. And because you're willing to wade through some complicated information with me, so we can discover the "gems" of information that will make a difference for you.

    In this report, we're going to go a little deeper into the science, in order to discover a truly new approach to solving your problem. What I'm going to show you now hasn't been on CNN- yet. It's not talked about much, even in the most sophisticated hair loss forums. But I consider it to be one of the most important advances in understanding how the hair follicle works- and how to make it work better.

    In the coming years, you will hear about a new molecule, and how it may be the "real" cause of follicle dysfunction and hair loss. But you're not going to wait years to learn about it.

    A better target than DHT?

    So what is this "mystery molecule" I want to show you? It's called Transforming Growth Factor, or TGF for short. Specifically, the "beta" form- TGF-β.

To understand its importance, we need to review what we know about DHT and hair loss. It's widely believed that DHT is the biggest cause of androgenetic alopecia. The makers of Propecia® will tell you it's
the only cause. But the new science tells us that's not true. And it explains a lot about why DHT inhibitors are not the final solution for most people.     Now, DHT is obviously involved in the process, or drugs like Propecia® wouldn't work at all. But understanding more about why it works- sometimes- will lead to better treatments. At least one researcher has also identified TGF-β as a mechanism of action for minoxidil. We may be looking at the real reason that minoxidil and Propecia® help hair growth.     Even more exciting, it's now possible to counteract TGF-β without drugs and their unwanted side effects.	.	.
		When anagen hair follicles were cultured with TGF-2, catagen-like change was markedly accelerated (b)
In androgenetic alopecia, we have what's called the hormone cascade, and more recently the "catagen cascade." Simply put, it looks like this:
Testosterone ==>  5 alpha-reductase ==> DHT

    DHT inhibitors work by inhibiting 5 alpha-reductase (5AR), an enzyme that converts testosterone to DHT. Without 5AR, testosterone doesn't convert. Less DHT gets to the follicle (and prostate). Less hair loss. For some, even new hair growth.

    So far so good. But there are problems. Because DHT inhibitors can cause side effects. DHT is needed for proper development of male sex organs in the fetus. It's also a factor in libido, and may well have other important positive effects in the body.

    Do we really want to get rid of DHT?

    Scientists in Germany, Korea, and Japan are saying no. In hair loss, there is a better target than DHT. A more selective target. One that produces no birth defects or loss of libido. What these scientists suggest is that another chemical, downstream from DHT, is what actually damages and shrinks the hair follicle.

    These researchers say the cascade actually looks like this:

    They propose that DHT is not the cause of hair loss and follicle atrophy; that the real problem is TGF-β. And the consensus is growing. Do these statements sound promising to you?

Click here or a review of important studies on TGF-β and hair loss

    (Were you aware until just now how important TGF-β is to the follicle cycle? Before I began looking at these related studies, I had no idea that this theory had gained such support in the scientific community. I find it curious that this is not more widely known.)

    What if we could leave DHT alone, and go after TGF-β directly? With a more selective target- a better target- we may see more effective treatments, and fewer- or even zero- side effects. Because TGF-β is apparently not good for anything except shrinking your follicles.

    So let's get rid of it! The sooner the better. But there are no drugs I can find that target TGF-β. (Hmmm... maybe that's why we don't hear more about it?)

    But here's the good news: there are at least two effective natural compounds that inhibit TGF-β. We know this from cancer research, and since last year, we know it directly from hair follicle research.

    What are these two natural compounds you can take today to inhibit this nasty chemical? I'll give you a hint: one is from apples. The other one may already be in your kitchen spice rack. Together, they show the ability to powerfully inhibit TGF-β.

    This is great news for women suffering from hair loss, for whom DHT inhibitors generally don't work. It's also great news for men, who may want the benefits of Propecia® without loss of libido and other potential side effects.

    Next time, you'll learn more about the science behind both of these natural TGF-β inhibitors, and how to get them into your diet and your follicles. Until then...

    Don’t you dare give up!

   
    David L. Kern
    New Health & Longevity
    www.applepoly.com/newscience
    © 2007-2010 New Health & Longevity

    P.S. Apple procyanidins are proven to strongly and safely inhibit TGF-β directly in the hair follicle. You should eat more fresh apples- organic if you can find them- along with other procyanidin-rich foods. But the best way to get far more procyanidins to inhibit TGF-β is to use our apple based Poly-GRO products.