Regrow hair
Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation
There is no treatment currently available to prevent or retard chemotherapy-induced alopecia. This paper shows how apple polyphenols can preserve hair and pr...
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Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth?
Eight out of nine critical hair growth pathways—unlocked by one compound? There’s simply no other hair growth solution—natural or synthetic—that activates th...
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Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Apple-derived procyanidin B2 therapy emerges here as the class of the field in natural hair growth options, with rigorous clinical trials and clear results i...
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The Effect of Apple (Malus sylvestris mill) as a Natural Ingredient to Prevent Hair Loss
This review study from Indonesia highlights evidence from human clinical trials, showing measurable hair regrowth in subjects with alopecia treated with appl...
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An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice
After three-week treatment with procyanidin-rich apple extract, hair length, weight, thickness, and density showed significant increases in both low and high...
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Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation
This study fills a critical gap in understanding how polyphenol-rich apple extracts stimulate hair growth at the cellular level.
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Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial
“We observed significant results in terms of increased hair growth, density, and keratin content, already after 2 months.” This is the first human clinical t...
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A randomized double-blind placebo-controlled clinical trial to evaluate the effect of an Annurca apple supplement formula in androgenic alopecia
This randomized, double-blind, placebo-controlled trial offers further clinical proof that oral apple polyphenols can slow hair loss and accelerate hair grow...
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Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
This study adds a unique layer to the growing body of research on apple polyphenols and hair growth. While many nutraceuticals claim benefits, apple procyani...
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Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss
This well-referenced Italian study on apple polyphenols tops out at 47 citations, spanning hair biology, polyphenol analytics, clinical trials, extraction me...
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Evaluation of the Efficacy and Safety of Topical Procyanidin B2 and Placebo in the Treatment of Androgenetic Alopecia in Men;
“We observed that the topical procyanidin B2 dimer is an effective and safe treatment option for the treatment of AGA.”
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The first clinical trial of topical application of procyanidin B-2 to investigate its potential as a hair growing agent
"Procyanidin B-2 therapy shows potential as a promising cure for male pattern baldness."
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