Activate anti-inflammatory genes
Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth?
Eight out of nine critical hair growth pathways—unlocked by one compound? There’s simply no other hair growth solution—natural or synthetic—that activates th...
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The Effect of Apple (Malus sylvestris mill) as a Natural Ingredient to Prevent Hair Loss
This review study from Indonesia highlights evidence from human clinical trials, showing measurable hair regrowth in subjects with alopecia treated with appl...
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An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice
After three-week treatment with procyanidin-rich apple extract, hair length, weight, thickness, and density showed significant increases in both low and high...
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Plant polyphenols as dietary antioxidants
If a new wonder drug could target 4 of the 5 leading causes of death, would you take it?
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The influence of different forms of apple products on all-cause mortality in patients with hypertension
Eating whole apples 3–6 times per week was linked to a 48% drop in death risk for hypertensive patients, highlighting the power of polyphenols in the peels.
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Flavonoid-Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease:
From the authors: “An improvement in vascular function was only seen after the high-flavonoid apple treatment... attributable to the high concentration of fl...
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Skin Moisturizing Activity of Unripe Apple (Immature Fruit of Malus pumila) in Mice
This study adds to a growing body of evidence supporting polyphenol-rich fruit extracts as bioactive agents for skin health. It complements prior research on...
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Association of flavonoids and flavonoid-rich foods with all-cause mortality:
In this 14 year follow-up study in older Australians, high proanthocyanidin intake brought mortality risk down nearly 31%. In those with early mortality risk...
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Anti-Aging Effects of Phloridzin, an Apple Polyphenol, on Yeast via the SOD and Sir2 Genes
"In the present study, we searched for phytochemicals from natural sources that possess significant anti-aging effects, and made further studies of the mecha...
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ANTI-AGING EFFECTS OF APPLE PROCYANIDINS
"These findings strongly indicate that APs showed anti-aging effects, such as anti-oxidative, anti-protein aggregation and pro-longevity effects, using model...
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The effects and associations of whole-apple intake on diverse cardiovascular risk factors:
“Whole-apple intake improves different CVD risk factors through the reduction of blood pressure, pulse pressure, total cholesterol, low-density lipoprotein c...
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Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties:
"What is now proved was once only imagined." — William Blake Researchers from India, Czech Republic, and the UK propose fruit polyphenols as dietary compoun...
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Polyphenols of Apples and Their Potential Health Benefits
This chapter remains a go-to primer for understanding the wide ranging biological effects of apple polyphenols, and a prequel to more targeted studies on UV ...
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A deep dive into the orchard of health:
“This review highlights the emerging role of apple polyphenols as multifunctional agents in the maintenance of physiological balance and healthy aging.”
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A comprehensive review on effective role of Apple polyphenols in the treatment of obesity, diabetes, and liver dysfunctions with some possible molecular mechanisms
Apple polyphenols possess strong antioxidant properties, reduce lipid accumulation, regulate glucose, and modulate inflammatory pathways—making them promisi...
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Apple Pomace Extract Induces Cell Proliferation and Increases Type I Collagen and Hyaluronan Production in Human Skin Fibroblasts In Vitro
The apple extract boosted collagen and hyaluronic acid—the molecules behind firm, hydrated skin—by activating the skin’s own repair genes.
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Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
This comprehensive review highlights CGA’s multi-targeted therapeutic potential across inflammation, oxidative stress, metabolic dysfunction, and neurodegene...
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