Research
Polyphenols of Apples and Their Potential Health Benefits
This chapter remains a go-to primer for understanding the wide ranging biological effects of apple polyphenols, and a prequel to more targeted studies on UV ...
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Fruits and Herbs as Potential Human Anti-Aging Compounds – A Review
“These results clearly suggest that, when applied to model organisms, APs demonstrated anti-aging properties, including anti-oxidative, anti-protein aggregat...
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Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults:
“This is the first meta-analysis to evaluate the effectiveness of oral dietary supplements for skin moisturizing in healthy adults.”
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A deep dive into the orchard of health:
“This review highlights the emerging role of apple polyphenols as multifunctional agents in the maintenance of physiological balance and healthy aging.”
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Evaluation of Safety of Excessive Intake and Efficacy of Long-term Intake of Beverages Containing Apple Polyphenols
In this 12 week randomized, controlled clinical trial, abdominal fat, waist and hip circumference, waist-to-hip ratio, and BMI all decreased significantly co...
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Administration of Apple Polyphenol Supplements for Skin Conditions in Healthy Women:
“Oral administration of AP inhibited pigmentation induced by UV irradiation in this human clinical study.”
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A comprehensive review on effective role of Apple polyphenols in the treatment of obesity, diabetes, and liver dysfunctions with some possible molecular mechanisms
Apple polyphenols possess strong antioxidant properties, reduce lipid accumulation, regulate glucose, and modulate inflammatory pathways—making them promisi...
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Apple Pomace Extract Induces Cell Proliferation and Increases Type I Collagen and Hyaluronan Production in Human Skin Fibroblasts In Vitro
The apple extract boosted collagen and hyaluronic acid—the molecules behind firm, hydrated skin—by activating the skin’s own repair genes.
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Whitening and Anti-wrinkle Effects of Apple Extracts
“Apple peel extract—concentrated for its active compounds—outperformed the rest in brightening and firming tests."
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Visceral Fat-Reducing Effect of Supplement Containing Apple Polyphenol and Oleanolic Acid in Healthy Japanese:
In a 12-week clinical trial, 29 healthy women saw statistically significant reductions in visceral fat (−6.0 cm²), weight (−2.7 kg), BMI (−1.1), and waist ci...
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Chlorogenic Acid Prevents UVA-Induced Skin Photoaging through Regulating Collagen Metabolism and Apoptosis in Human Dermal Fibroblasts
“Our study, for the first time, demonstrates that chlorogenic acid (CGA) has protective effects during skin photoaging, especially triggered by UVA-irradiati...
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Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
This comprehensive review highlights CGA’s multi-targeted therapeutic potential across inflammation, oxidative stress, metabolic dysfunction, and neurodegene...
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Apple Polyphenols Influence Cholesterol Metabolism in Healthy Subjects with Relatively High Body Mass Index
“The visceral fat area and the level of adiponectin in the group administered apple polyphenols improved in comparison with the control group.”
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Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebo-controlled, double-blind study
"The reality is, aging comes from the inside. How your skin looks depends on how your internal cells are working. Your skin is made from the inside out." - D...
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Evaluation of the Efficacy and Safety of Topical Procyanidin B2 and Placebo in the Treatment of Androgenetic Alopecia in Men;
“We observed that the topical procyanidin B2 dimer is an effective and safe treatment option for the treatment of AGA.”
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The first clinical trial of topical application of procyanidin B-2 to investigate its potential as a hair growing agent
"Procyanidin B-2 therapy shows potential as a promising cure for male pattern baldness."
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